Potential Therapeutics For Treating Type 2 Diabetes Mellitus

Bromophenols have been identified as potential therapeutics for treating type 2 diabetes mellitus (T2DM) due to their suspected tyrosine phosphatase 1B (PTP1B) inhibitory activity. A new series of bromophenol analogues will be synthesised and their PTP1B inhibitory activity will be tested in in vitro enzymatic assays to elucidate their mechanism of action as PTP1B inhibitors. Background and Introduction Type 2 diabetes mellitus (T2DM) is a metabolic disease that is caused by insulin resistance of the peripheral tissues and impaired insulin secretion of the pancreatic ÃŽ ² cells.1 Both conditions result in reduced glycemic control, which can lead to hyperglycemia. Despite the availability of a wide range of anti-diabetic drugs to treat T2DM,†¦show more content†¦Bromophenols have attracted much attention as potential PTP1B inhibitors due to their suspected anti-diabetic activity.4 Bromophenols occur naturally in marine organisms such as algae, mollusks and jellyfish. ( ±)-Polysiphenol (1, figure 1) is an example of a bromophenol that can be extracted from the marine algae Polisiphonia Ferulecea.5 After the Braddock group successfully achieved the first total synthesis of ( ±)-polysiphenol and the separation of its enantiomers, they collaborated with the Woscholski group to test their inhibitory activity in PTP1B enzymatic assays.6,7 Both enantiomers of polysiphenol were essentially found to be identical in PTP1B inhibitory activity. Thus polysiphenol, as single enantiomers, cannot be responsible for the observed inhibition. This implicates a chemical change of polysiphenol into a non-chiral form is likely to take place under the conditions of the assay. One possibility is the formation of a para-quinone methide species (4, figure 1), which in turn can tautomerise into an ortho-quinone methide species (5, figure 1). Thus there are various possible reactive species that might be responsible for the observed inhibition of PTP1B. The formation of quinones highlights a red flag in drug discovery due to their highly reactive nature. Quinones are Michael acceptors that are known to cause toxicity in vivo by covalently binding to nucleophilic sites on proteins and DNA.8 Consequently, quinones

The Gibbs Reflective Cycle And Development Of Self, The...

â€Å"Professional development involves reflecting on values, your commitment to your own, and the values of others† states Ghaye and Lillyman (2011). This also involves reflecting on the things we do, why we do it and how. The role of reflection as stated by Ghaye and Lillyman is about the development of self, the collaborative team and the context of healthcare. As a nurse, professional development is constantly being improved to make ourselves better nurses and provide better-quality care to our patients. To help with this development, reflecting and analysing our learning and actions benefits our professionalism and values. The aim of this essay is to critically analyse a learning objective was created in the last pre-graduate clinical placement. The Gibbs Reflective Cycle is used as a framework to help to analyse the learning objective (Gibbs, 1988). This will include a framework with six headings; Description, Feelings, Initial evaluation, Analysis, Conclusions and Actio n plan. The learning objective that I choose was to have an increased knowledge and skills in the care for patient post-operatively. Within this learning objective was identifying key assessments, medications and potential post-operative complications involved with caring for a patient post-operatively. As I was in a surgical ward I had a lot of opportunities to complete this learning objective as I cared for many patients who needed post-operative care. Description To complete this learning objective,Show MoreRelatedReflective Account of ....10187 Words   |  41 Pagesworking in the ED are competent in the provision of emergency cares and function as the main front liner care provider that includes provision of emergency treatment, stabilization, definitive care and function as an important component of the Trauma Team (Ministry of Health Malaysia (MOH), 2005). ED function as a core business at government hospitals, it plays a crucial role in the emergency treatment of patients. In addition the department also plays a role in pre hospital care, call center and trainingRead MoreBusiness Functions in Context Notes Essay10972 Words   |  44 PagesB203 Business Functions in Context – Revision Notes Introduction * Communities of Practice (Wenger, 2007) - are groups of people the come together to share knowledge and experiences and learn from one another whilst providing a social context for that work. Three characteristics are crucial: 1. The Domain - It has an identity defined by a shared domain of interest. Membership implies a commitment to this and therefore a shared competence that distinguishes members from other peopleRead MoreDeveloping Management Skills404131 Words   |  1617 PagesIntroduction 1 PART I 1 2 3 PERSONAL SKILLS 44 Developing Self-Awareness 45 Managing Personal Stress 105 Solving Problems Analytically and Creatively 167 PART II 4 5 6 7 INTERPERSONAL SKILLS 232 233 Building Relationships by Communicating Supportively Gaining Power and Influence 279 Motivating Others 323 Managing Conflict 373 PART III GROUP SKILLS 438 8 Empowering and Delegating 439 9 Building Effective Teams and Teamwork 489 10 Leading Positive Change 533 PART IV Read MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pagesand Moods 97 Personality and Values 131 Perception and Individual Decision Making 165 Motivation Concepts 201 Motivation: From Concepts to Applications 239 3 The Group 9 10 11 12 13 14 15 Foundations of Group Behavior 271 Understanding Work Teams 307 Communication 335 Leadership 367 Power and Politics 411 Conflict and Negotiation 445 Foundations of Organization Structure 479 v vi BRIEF CONTENTS 4 The Organization System 16 Organizational Culture 511 17 Human Resource Policies

The 10 Coolest Dinosaur Names

Why All Sales Tax Should Be Banned Forever - 835 Words

Why should all sales tax be banned forever Everyone does shopping. It’s the way Americans live their daily life. It is from getting doughnuts at Quiktrip to buying an iPad. All these goods have to have a transaction in order for you to own it. Sales tax is an important part of this transaction. Everyday, people pay sales tax everyday for their purchases. Some states have high rates, and some states have low sales tax rates. Sales tax is a tax imposed by the government at the point of sale on retail goods and services.(Investopedia Contributors) It is collected by the retailer and passed on to the state.(Investopedia Contributors) Every Time you swipe your credit card, according to your state’s law, a percentage of the total amount worth of the goods is paid to the government. Inside the City limits of Tulsa, the sales tax and use tax is 8.517%.(â€Å"sales tax in Tulsa†) But when you go to another state and shop, such as california, the standard statewide rate of 7.50%.(â€Å"California City $ County Sales $ Use Tax Rates†) But when you shop online, it’s a different case, whether to pay sales tax depends on the retailer’s location. The current default rule throughout the United States is that you must collect sales tax on Internet sales to customers in those states where your business has a â€Å"physical presence†. (Steingold) From the point of shoppers, sales tax is annoying and should be repealed forever. Instead of just straight up removing the sales tax, the income tax should beShow MoreRelatedPros and Cons of Drug Legalization Essay1476 Words   |  6 PagesThe Pros and Cons of Drug Legalization Should drugs be legalized ? Drugs are resources that are capable of affecting theAmerican economy in many ways--both positively and negatively. Drugs often have a bad name even though they help us everyday in medical cases. and the drugs with the worst reputations are not the most abused drugs One may benefit from the legalization of drugs in many ways, while others would suffer greatly. Almost every person in the United States has their ownRead MoreHunting : The Benefits Of Wildlife Conservation1237 Words   |  5 Pagesthrough license sales and the excise tax on hunting equipment† (â€Å"Benefits† 1). There have been many federal efforts to create funding for conservation from hunting. The Pittman-Robertson act was established to raise funds for conservation by levying taxes and fees (Gooch 2). The Pittman- Robertson act has raised $10.1 billion since it was enacted in 1937 (Guiden 3). This money is used for conservation all over the country. According to The U.S. Fish and Wildlife Service â€Å"the sale of hunting licenseRead MoreCollege Sports Gambling2514 Words   |  11 PagesWith all of the controversy of gambling in college sports, why is the issue still an issue? The answer is money. There were actions taken towards this by Congress, but the problem is that it was never completely abolished. Congress had made the mistake of creating a way around it. It is now commonly referred to as the Las Vegas loophole. They outlawed the betting nationwide with the exception of one state, one state that is the capital of gambling, Nevada. This has caused few changesRead MoreFiji Water Case Study13053 Words   |  53 Pagesbefore we had water in bottles. It is unnecessary. When you see water imported from Fiji in plastic bottles, you know it’s bad for the environment all round.† Lee Rhiannon, Australia’s Greens MP3 â€Å"I think the world is slowly going insane. No thanks but I prefer water in bottles, that way you know it’s clean and you know, healthy. Not a sacrifice people should make when plastic bags are still rampant. Those Greens are extremists and I don’t see this ‘tap water alternative’ ever being viable.† AnthonyRead MoreFor Against by L.G. Alexander31987 Words   |  128 PagesFOR ADVANCED STUDENTS OF ENGLISH L.G.ALEXANDER .... †¢Ã¢â‚¬ ¢Ã¢â‚¬ ¢ †¢Ã¢â‚¬ ¢Ã¢â‚¬ ¢ ~ LONGMAN WNGMANGROUP UK UMITED Longman House, Burnt Mill, Harlow, Essex CM20 2iE, England and Associated Companies throughout the world  © Longman Group Ltd. 1968 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the PublishersRead MoreAnalylis Primark22310 Words   |  90 Pages PRIMARK Executive Summary This report consist of Primark Company‟s Strategic aspects. It contain detail analysis of Primark policies and future aspects. All strategies are derived accordingly the current market situations and competitive environment. So to round things off, Primark overall are not all bad but not brilliant. It s all very well having good value but if getting to the stock itself is such a deterring and unwelcome challenge then there is little point. Personally, I like to shopRead MoreModern History.Hsc.2012 Essay25799 Words   |  104 Pagespolicies / philosophies, many conservative points of view lost credibility and became unpopular, such as: * either pro-big-business or laissez faire (republican) economic policies, which had led to unsustainable and unbalanced rapid growth, * tax cuts for rich which had led to maldistribution of income and dangerously speculative investment, * protectionism (tariffs) * emphasis on ‘rugged individualism’ and Darwinist competition (‘survival of the fittest’) * opposition to reformRead MoreVarian Solution153645 Words   |  615 Pagesreservation price the consumer will demand one apartment, at any price above the reservation price the consumer will demand zero apartments, and exactly at the reservation price the consumer will be indiï ¬â‚¬erent between having zero or one apartment. You should also observe that when demand curves have the â€Å"staircase† shape used here, there will typically be a range of prices where supply equals demand. Thus we will ask for the the highest and lowest price in the range. 1.1 (3) Suppose that we have 8Read MoreWe Must Obey Our Elders17194 Words   |  69 PagesShould we OBEY our Elders A Photo of an Elder! A Tale of Correction ï‚ ©Ã¯  ´ By Ray Walter Swangkee ― The Colorful Peacock from Angel Ridge, Box 305H2, King’s Mountain, Kentucky 40442 The Divided States of United Lies! My E-mail Address is: theking@alltel.net, as in: â€Å"The King at TELL ALL, dot, Network of Truth.† Please Visit the most Beautiful, Enlightening, and Inspiring Website on the Internet, at: www.ThePeacock.com â€Å"O my Son, no one likes to Obey any Person that he or sheRead MoreCase Studies67624 Words   |  271 Pagesto use a specific analytical procedure to examine an organisation; others provide less structure, expecting students to learn by developing their own unique analytical method. Still other instructors believe that a moderately structured framework should be used to analyse a firm’s situation and make appropriate recommendations. Your lecturer or tutor will determine the specific approach you take. The approach we are presenting to you is a moderately structured framework. We divide our discussion

Night World Dark Angel Chapter 10 Free Essays

string(42) " things were going to turn out all right\." â€Å"But only if you absolutely swear to me you didn’t do it.† â€Å"Oh, how many times? I’ve been telling you all week I didn’t. I never said a word to her. We will write a custom essay sample on Night World : Dark Angel Chapter 10 or any similar topic only for you Order Now I swear.† The first voice, which sounded taut and a little unbalanced, was Tanya’s. The second was Kim the Gymnast’s. Despite her brave words, Kim sounded scared. (Angel? What’s going on?) (Trouble.) â€Å"Okay,† Tanya’s voice was saying. â€Å"Then this is your chance to prove it by helping me.† â€Å"Tan, look. Look. I’m sorry about you and David breaking up. But maybe it’s not Gillian’s fault-â€Å" â€Å"It’s completely her fault. The stuff with Bruce was over. You know that. There was no reason for David to ever find out-until she opened her mouth. And as for how she found out-â€Å" â€Å"Not again!† Kim the Gymnast sounded ready to scream. â€Å"I didn’t do it.† â€Å"All right. I believe you.† Tanya’s voice was calmer. â€Å"So in that case there’s no reason for us to fight. We’ve got to stick together. Hand me that brush, will you?† There was silence for a moment, and Gillian could imagine Tanya brushing her dark hair to a higher gloss, looking in a mirror approvingly. â€Å"So what are you going to do?† Kim’s voice asked. â€Å"Get both of them. In a way, I hate him more. I promised he’d be sorry if he dumped me, and I always keep my promises.† Squashed between the heavy, swaying clothes on her right and left, Gillian had a wild and almost fatal impulse to giggle. She knew what was going on. It was just such a †¦ a sitcom situation that she had a hard time making herself believe in it. Here she was, listening to two people who were actually plotting against her. She was overhearing their plans to get her. It was†¦ absurd. Bad mystery novel stuff. And it was happening anyway. She made a feeble attempt to get back to reality, straightening up slightly. (Angel-people don’t really do these revenge things. Right? They’re just talking. And-I mean, I can’t even believe I’m hearing all this. It’s so †¦ so ridiculous†¦) (You’re overhearing it because I brought you here. You have an invisible friend who can lead you to the right place at the right time. And you’d better believe that people carry out these â€Å"revenge things.† Tanya’s never made a plan that she hasn’t carried through.) (The future executive.) Gillian thought it faintly. (Future CEO. She’s deadly serious, kid. And she’s smart. She can make things happen.) Gillian no longer felt like giggling. When she pressed her ear against the wall again, it was clear she’d missed some of the conversation. â€Å"†¦ David first?† Kim the Gymnast was saying. â€Å"Because I know what to do with him. He wants to get into Ohio University, you know? He sent the application in October. It was already going to be a little hard because his grades aren’t great, but he scored really high on the SATs. It was hard, but I’m going to make it†¦Ã¢â‚¬  There was a pause and Tanya’s voice seemed to mellow and sweeten. â€Å"Absolutely impossible.† â€Å"How?† Kim sounded shaken. â€Å"By writing to the university. And to our principal and to Ms. Renquist, the English lit teacher, and to David’s grandpa, who’s supposed to be giving him money to go to college.† â€Å"But why? I mean, if you say something nasty, they’ll just think it’s sour grapes-â€Å" â€Å"I’m going to tell them he passed English lit last year by cheating. We had to turn in a term paper. But he didn’t write the paper he turned in. It was bought. From a college guy in Philadelphia.† Kim’s breath whooshed out so loudly that Gillian could hear it. â€Å"How do you know?† â€Å"Because I arranged it, of course. I wanted him to bring his grades up, to get into a university. To make something of himself. But of course he can never prove all that. He’s the one that paid for it.† A silence. Then Kim said, with what sounded like forced lightness, â€Å"But, Tan, you could ruin his whole life†¦Ã¢â‚¬  â€Å"I know.† Tanya’s voice was serene. Satisfied. â€Å"But†¦ well, what do you want me to do?† â€Å"Be ready to spread the word. That’s what you do best, isn’t it? I’ll get the letters written by Monday. And then on Monday you can start telling people-because I want everyone to know. Prime that grapevine!† Tanya was laughing. â€Å"Okay. Sure. Consider it done.† Kim sounded more scared than ever. â€Å"Uh, look, I’d better get back downstairs now-can I use the brush a second?† â€Å"Here.† A clatter. â€Å"And, Kim? Be ready to help me with Gillian, too. I’ll let you know what I’ve got in mind for her.† Kim said, â€Å"Sure,†-faintly. Then there were a few more clatters and the sound of a door rattling open and shut. Then silence. Gillian stood in the stuffy closet. She felt physically sick. As if she’d found something loathsome and slimy and unclean writhing under her bed. Tanya was crazy-and evil. Gillian had just seen into a mind utterly twisted with hatred. And smart. Angel had said it. (Angel, what do I do? She really means it, doesn’t she? She’s going to destroy him. And there isn’t anything I can do about it.) (There may be something.) (She’s not going to listen to reason. I know she’s not. Nobody’s going to be able to talk her out of it. And threats aren’t any good-) (I said, there may be something you can do.) Gillian came back to herself. (What?) (It’s a little complicated. And†¦ well, the truth is, you may not want to do it, kid.) (I would do anything for David.) Gillian’s response was instant and absolute. Strange, how there were some things you were so sure of. (Okay. Well, hold that thought. I’ll explain everything when we get home-which we should do fast. But first I want you to get something from that bathroom.) Gillian felt calm and alert, like a young soldier on her first mission in enemy territory. Angel had an idea. As long as she did exactly what Angel said, things were going to turn out all right. You read "Night World : Dark Angel Chapter 10" in category "Essay examples" She went into the bathroom and followed Angel’s instructions precisely without asking why. Then she went to get David to take her home from the party. â€Å"I’m ready. Now tell me what I can do.† Gillian was sitting on her bed, wearing the pajamas with little bears on them. It was well after midnight and the house was quiet and dark except for the lamp on her night stand. â€Å"You know, I think you are ready.† The voice was quiet and thoughtful-and outside her head. In the air about two feet away from the bed, a light began to grow. And then it was Angel, sitting lotus style, with his hands on his knees. Floating lotus style. He was about level with Gillian’s bed and he was looking at her searchingly. His face was earnest and calm, and all around him was a pale, changing light like the aurora borealis. As always, Gillian felt a physical reaction at the first sight of him. A sort of shock. He was so beautiful, so unearthly, so unlike anyone else. And right now his eyes were more intense than she had ever seen them. It scared her a little, but she pushed that-and the physical reaction-away. She had to think of David. David, who’d so trustingly taken her home when she â€Å"got sick† an hour ago, and who right now had absolutely no idea what was in store for him on Monday. â€Å"Just tell me what to do,† she said to Angel. She was braced. She had no idea what it would take to stop Tanya, but it couldn’t be anything pleasant-or legal. Didn’t matter. She was ready. So Angel’s words were something of a letdown. â€Å"You know you’re special, don’t you?† â€Å"Huh?† â€Å"You’ve always been special. And underneath, you’ve always known it.† Gillian wasn’t sure what to say. Because it sounded terribly cliche-but it was true. She was special. She’d had a near-death experience. She’d come back with an angel. Surely only special people did that. And her popularity at school-everyone there certainly thought she was special. But her own inner feeling had started long before that, sometime in childhood. She’d just imagined that everybody felt that way†¦ that they were different from others, maybe better, but certainly different. â€Å"Well, everybody does feel that way, actually,† Angel said, and Gillian felt a little jolt. She always felt it when she suddenly remembered her thoughts weren’t private anymore. Angel was going on. â€Å"But for you it happens to be true. Listen, what do you know about your great-grandma Elspeth?† â€Å"What?† Gillian was lost. â€Å"She’s an old lady. And, um, she lives in England and always sends me Christmas presents†¦Ã¢â‚¬  She had a vague memory of a photograph showing a woman with white hair and white glasses, a tweed skirt and sensible shoes. The woman held a Pekingese in a little red jacket. â€Å"She grew up in England, but she was born American. She was only a year old when she was separated from her big sister Edith, who was raising her. It happened during World War One. Everyone thought she had no family, so she was given to an English couple to raise.† â€Å"Oh, really? How interesting.† Gillian was not only bewildered but exasperated. â€Å"But what on earth-â€Å" â€Å"Here’s what it’s got to do with David. Your great-grandma didn’t grow up with her real sister, with her real family. If she had, she’d have known her real heritage. She’d have known†¦Ã¢â‚¬  â€Å"Yes?† â€Å"That she was born a witch.† There was a long, long silence. It shouldn’t have been so long. After the first second Gillian thought of things to say, but somehow she couldn’t get them past the tightness of her throat. She ought to laugh. That was funny, the idea of Great-grandma, with her sensible shoes, being a witch. And besides, witches didn’t exist. They were just stories- -like angels- -or examples of New Age grown-ups acting silly. â€Å"Angels,† Gillian gasped in a strangled voice. She was beginning to feel wild inside. As if rules were breaking loose. Because angels were true. She was looking at one. He was floating about two and a half feet off the floor. There was absolutely nothing under him and he could hear her thoughts and disappear and he was real. And if angels could be real†¦ Magic happens. She’d seen that on a bumper sticker somewhere. Now she clapped both hands to her mouth. There was something boiling up inside her and she wasn’t sure if it was a scream or a giggle. â€Å"My great-grandma is a witch?† â€Å"Well, not exactly. She would be if she knew about her family. That’s the key, you see-you have to know. Your great-grandma has the blood, and so does your grandma, and so does your mom. And so do you, Gillian. And now†¦ you know.† The last words were very gentle, very deliberate. As if Angel were delicately putting into place the last piece of a puzzle. Gillian’s laughter had faded. She felt dizzy, as if she had unexpectedly come to the edge of a cliff and looked over. â€Å"I’m†¦ I’ve got the blood, too.† â€Å"Don’t be afraid to say it. You’re a witch.† â€Å"Angel†¦Ã¢â‚¬  Gillian’s heart was beating very hard suddenly. Hard and slow. â€Å"Please †¦ I don’t really understand any of this. And†¦ well, I’m not.† â€Å"A witch? You don’t know how to be, yet. But as a matter of fact, kid, you’re already showing the signs. Do you remember when that mirror broke in the downstairs bathroom?† â€Å"And when the window broke in the cafeteria. You asked me if I did those things. I didn’t. You did. You were angry and you lashed out with your power†¦ but you didn’t realize it.† â€Å"Oh, God,† Gillian whispered. â€Å"It’s a frightening thing, that power. When you don’t know how to use it, it can cause all kinds of damage. To other people-and to you. Oh, kid, don’t you understand? Look at what’s happened to your mother.† â€Å"What about my mother?† â€Å"She †¦ is †¦ a †¦ witch. A lost witch, like you. She’s got powers, but she doesn’t know how to channel them, she doesn’t understand them, and they terrify her. When she started seeing visions-â€Å" â€Å"Visions!† Gillian sat straight up. It was as if a light had suddenly gone on in her head, illuminating five years of her life. â€Å"Yeah.† Angel’s violet eyes were steady, his face grim. â€Å"The hallucinations came before the drinking, not after. And they were psychic visions, images of things that were going to happen, or that might have happened, or that happened a long time ago. But of course she didn’t understand that.† â€Å"Oh, God. Oh, my God.† Electricity was running up and down Gillian’s body, setting her whole skin tingling. Tears stung in her eyes-not tears of sadness, but of pure, shocking revelation. â€Å"That’s it. That’s it. Oh, God, we’ve got to help her. We’ve got to tell her-â€Å" â€Å"I agree. But first we have to get you under control. And it’s not exactly a thing you can just spring on her without any warning. You could do more harm than good that way. We’ve got to build up to it.† â€Å"Yes. Yes, I see that. You’re right.† Gillian blinked rapidly. She tried to calm her breathing, to think. â€Å"And just at the moment, she’s stable. A little depressed, but stable. She’ll wait until after Monday. But Tanya won’t.† â€Å"Tanya?† Gillian had nearly forgotten the original discussion. â€Å"Oh, yeah, Tanya. Tanya.† David, she thought. â€Å"There is something very practical you can do about Tanya-now that you know what you are.† â€Å"Yes. All right.† Gillian wet her lips. â€Å"Do you think Dad will come back if Mom realizes what she is and gets it all together?† â€Å"I think there’s a good possibility. But listen to me. To take care of Tanya-â€Å" â€Å"Angel.† A slow coil of anxiety was unrolling in Gillian’s stomach. â€Å"Now that I think about it †¦ I mean, aren’t witches bad? Shouldn’t you-well, disapprove of this?† Angel put his golden head in his hands. â€Å"If I thought it was bad would I be here guiding you through it?† Gillian almost laughed. It was so incongruous- the pale northern lights aura around him and the sound of him talking through clenched teeth. Then a thought struck her. She spoke hesitantly and wonderingly. â€Å"Did you come here to guide me through it?† He lifted his head and looked at her with those unearthly eyes. â€Å"What do you think?† Gillian thought that the world wasn’t exactly what she had thought. And neither were angels. The next morning she stood and looked at herself in the mirror. She’d done this after Angel had first come to her and made her cut her hair-she’d wanted to look at her new self. Now she wanted to look at Gillian the witch. There wasn’t anything overtly different about her. But now that she knew she seemed to see things she hadn’t noticed before. Something in the eyes-some ancient glimmer of knowledge in their depths. Something elfin in the face, in the slant of the cheekbones. A remnant of faery. â€Å"Stop gazing and come shopping,† Angel said, and light coalesced beside her. â€Å"Right,† Gillian said soberly. Then she tried to wiggle her nose. Downstairs, she borrowed the keys to her mother’s station wagon and bundled up. It was an icy-fresh day and the whole world sparkled under a light dusting of new snow. The air filled Gillian’s lungs like some strange potion. (I feel very witchy.) She backed the car out. (Now where do we go? Houghton?) (Hardly. This isn’t the kind of shopping you do at a mall. Northward, ho! We’re going to Woodbridge.) Gillian tried to remember Woodbridge. It was a little town like Somerset-but smaller. She’d undoubtedly driven through it at some point in her life. (We need to go shopping in Woodbridge to take care of Tanya?) (Just drive, dragonfly.) Woodbridge’s main street ended in a town square bordered by dozens of decorated trees. The stores were trimmed with Christmas lights. It was a postcard scene. (Okay. Park here.) Gillian followed Angel’s directions and found herself in the Woodbridge Five and Ten, an old-style variety store, complete with creaking wooden floorboards. She had the terrifying feeling that time had gone back about fifty years. The aisles were tight and the shelves were jammed with baskets full of goods. There was a musty smell. Beyond asking questions, she stared dreamily at a jar of penny candy. (Head on to the back. All the way. Open that door and go through to the back room.) Gillian nervously opened the rickety door and peered into the room beyond. But it was just another store. It had an even stranger smell, partly delicious, partly medicinal, and it was rather dimly lit. â€Å"Uh, hello?† she said, in response to Angel’s urging. And then she noticed movement behind a counter. A girl was sitting there. She was maybe nineteen and had dark brown hair and an interesting face. It was quite ordinary in shape and structure-a country girl sort of face-but the eyes were unusually vivid and intense. â€Å"Um, do you mind if I look around?† Gillian said, again in response to Angel. â€Å"Go right ahead,† the girl said. â€Å"I’m Melusine.† She watched with a perfectly friendly and open curiosity as Gillian moseyed around the shelves, trying to look as if she knew what she was looking for. Everything she saw was strange and unfamiliar-rocks and herby-looking things and different colored candles. (It’s not here.) Angel’s voice was resigned. (We’re going to have to ask her.) â€Å"Excuse me,† Gillian said a moment later, approaching the girl diffidently from the other side. â€Å"But do you have any Dragon’s Blood? The-activated kind?† The girl’s face changed. She looked at Gillian very sharply. Then she said, â€Å"I’m afraid I’ve never heard of anything like that. And I wonder what makes you ask.† Gooseflesh blossomed on Gillian’s arms. She had the sudden, distinct feeling that she was in danger. How to cite Night World : Dark Angel Chapter 10, Essay examples

Missouri Trespass Laws free essay sample

A person commits the crime of trespass in the first degree if he knowingly enters unlawfully or knowingly remains unlawfully in a building or inhabitable structure or upon real property. 2. A person does not commit the crime of trespass in the first degree by entering or remaining upon real property unless the real property is fenced or otherwise enclosed in a manner designed to exclude intruders or as to which notice against trespass is given by: (1) Actual communication to the actor; or (2) Posting in a manner reasonably likely to come to the attention of intruders. . Trespass in the first degree is a class B misdemeanor. A person commits the offense of trespass in the second degree if he enters unlawfully upon real property of another. This is an offense of absolute liability. 2. Trespass in the second degree is an infraction. Private land, permission of owner needed to fish, hunt, or trap, penalty for violation. We will write a custom essay sample on Missouri Trespass Laws or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page (578. 520) 1. No person shall fish, hunt, or trap upon or retrieve wildlife from any private land that is not owned or in the possession of such person without permission from the owner or lessee of such land. . Any person who violates the provisions of this section is guilty of a class B misdemeanor. Any person who knowingly enters or remains on private property for the purpose of hunting, fishing, trapping, or retrieving wildlife in violation of subsection 1 of this section may, in addition to the penalty in subsection 2 of this section, be required by the court to surrender and deliver any license or permit issued by the department of conservation to hunt, fish, or trap. The court shall notify the conservation commission of any conviction under this section and request the commission take necessary action to revoke all privileges to hunt, fish, or trap for at least one year from the date of conviction. Posting of property against trespassers, purple paint used to mark streets and posts, requirementsentry on posted property is trespassing in first degree, penalty. (569. 145) In addition to the posting of real property as set forth in section 569. 40, the owner or lessee of any real property may post the property by placing identifying purple marks on trees or posts around the area to be posted. Each purple mark shall be: (1) A vertical line of at least eight inches in length and the bottom of the mark shall be no less than three feet nor more than five feet high. Such marks shall be placed no more than one hundred feet apart and shall be readily visible to any person approaching the property; or (2) A post capped or otherwise marked on at least its top two inches. The bottom of the cap or mark shall be not less than three feet but not more than five feet six inches high. Posts so marked shall be placed not more than thirty-six feet apart and shall be readily visible to any person approaching the property. Prior to applying a cap or mark which is visible from both sides of a fence shared by different property owners or lessees, all such owners or lessees shall concur in the decision to post their own property.

Sexual Orientation free essay sample

Homosexuality (from Ancient Greek , meaning same, and Latin sexus, meaning sex) is romantic attraction, sexual attraction or sexual behavior between members of the same sex or gender. As an orientation, homosexuality refers to an enduring pattern of or disposition to experience sexual, affectionate, or romantic attractions primarily or exclusively to people of the same sex. It also refers to an individuals sense of personal and social identity based on those attractions, behaviors expressing them, and membership in a community of others who share them. [1][2] Along with bisexuality and heterosexuality, homosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. [1] There is no consensus among scientists about why a person develops a particular sexual orientation;[1] however, biologically-based theories for the cause of sexual orientation are favored by experts,[3] which point to genetic factors, the early uterine environment, or both in combination. [4] There is no substantive evidence which suggests parenting or early childhood experiences play a role when it comes to sexual orientation;[4] when it comes to same-sex sexual behavior, shared or familial environment plays no role for men and minor role for women. We will write a custom essay sample on Sexual Orientation or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page [5] While some hold the view that homosexual activity is unnatural,[6][7] research has shown that homosexuality is an example of a normal and natural variation in human sexuality and is not in and of itself a source of negative psychological effects. [1][8] Most people experience little or no sense of choice about their sexual orientation. [1] There is insufficient evidence to support the use of psychological interventions to change sexual orientation. [9] The most common terms for homosexual people are lesbian for females and gay for males, though gay is also used to refer generally to both homosexual males and females. The number of people who identify as gay or lesbian and the proportion of people who have same-sex sexual experiences are difficult for researchers to estimate reliably for a variety of reasons, including many gay people not openly identifying as such due to homophobia and heterosexist discrimination. [10] Homosexual behavior has also been documented and is observed in many non-human animal species. Many gay and lesbian people are in committed same-sex relationships, though only recently have census forms and political conditions facilitated their visibility and enumeration. [16][17][18][19][20][21][22][23][24][25] These relationships are equivalent to heterosexual relationships in essential psychological respects. [2] Homosexual relationships and acts have been admired, as well as condemned, throughout recorded history, depending on the form they took and the culture in which they occurred. [26] Since the end of the 19th century, there has been a global movement towards increased visibility, recognition, and legal rights for homosexual people, including the rights to marriage and civil unions, adoption and parenting, employment, military service, equal access to health care, and the introduction of anti-bullying legislation to protect gay minors. HISTORY Societal attitudes towards same-sex relationships have varied over time and place, from expecting all males to engage in same-sex relationships, to casual integration, through acceptance, to seeing the practice as a minor sin, repressing it through law enforcement and judicial mechanisms, and to proscribing it under penalty of death. People with a homosexual orientation can express their sexuality in a variety of ways, and may or may not express it in their behaviors. [1] Many have sexual relationships predominately with people of their own gender identity, though some have sexual relationships with those of the opposite gender, bisexual relationships, or none at all (celibate). [1] The Kinsey scale attempts to describe a persons sexual history or episodes of their sexual activity at a given time. It uses a scale from 0, meaning exclusively heterosexual, to 6, meaning exclusively homosexual. It is based on actual sexual behavior surveys. Research indicates that many lesbians and gay men want, and succeed in having, committed and durable relationships. For example, survey data indicate that between 40% and 60% of gay men and between 45% and 80% of lesbians are currently involved in a romantic relationship. [110] Survey data also indicate that between 18% and 28% of gay couples and between 8% and 21% of lesbian couples in the U. S. have lived together ten or more years. [110] Studies have found same-sex and opposite-sex couples to be equivalent to each other in measures of satisfaction and commitment in relationships, that age and gender are more reliable than sexual orientation as a predictor of satisfaction and commitment to a relationship, and that people who are heterosexual or homosexual share comparable expectations and ideals with regard to romantic relationships GENERAL Science has looked at the causes of homosexuality, and more generically the causes of human sexual orientation, with the general conclusions being related to biological and environmental factors. The biological factors that have been researched are genetic and hormonal, particularly during the fetal developmental period, that influence the resulting brain structure, and other characteristics such as handedness. [3][4] There are a wide range of environmental factors (sociological, psychological, or early uterine environment), and various biological factors, that may influence sexual orientation; though many researchers believe that it is caused by a complex interplay between nature and nurture, they favor biological models for the cause. Sexual orientation change efforts There are no studies of adequate scientific rigor to conclude whether sexual orientation change efforts work to change a persons sexual orientation. Those efforts have been controversial due to tensions between the values held by some faith-based organizations, on the one hand, and those held by LGBT rights organizations and professional and scientific organizations and other faith-based organizations, on the other. [9] The longstanding consensus of the behavioral and social sciences and the health and mental health professions is that homosexuality per se is a normal and positive variation of human sexual orientation, and therefore not a mental disorder. [9] The American Psychological Association says that most people experience little or no sense of choice about their sexual orientation. [156] Some individuals and groups have promoted the idea of homosexuality as symptomatic of developmental defects or spiritual and moral failings and have argued that sexual orientation change efforts, including psychotherapy and religious efforts, could alter homosexual feelings and behaviors. Many of these individuals and groups appeared to be embedded within the larger context of conservative religious political movements that have supported the stigmatization of homosexuality on political or religious grounds. No major mental health professional organization has sanctioned efforts to change sexual orientation and virtually all of them have adopted policy statements cautioning the profession and the public about treatments that purport to change sexual orientation. Physical The terms Men who have sex with men (MSM) and women who have sex with women (WSW) refer to people who engage in sexual activity with others of the same sex regardless of how they identify themselves—as many choose not to accept social identities as lesbian, gay and bisexual. [177][178][179][180][181] These terms are often used in medical literature and social research to describe such groups for study, without needing to consider the issues of sexual self-identity. The terms are seen as problematic, however, because they obscure social dimensions of sexuality; undermine the self-labeling of lesbian, gay, and bisexual people; and do not sufficiently describe variations in sexual behavior. [182] MSM and WSW are sexually active with each other for a variety of reasons with the main ones arguably sexual pleasure, intimacy and bonding. In contrast to its benefits, sexual behavior can be a disease vector. Safe sex is a relevant harm reductionphilosophy. [183] The United States currently prohibits men who have sex with men from donating blood because they are, as a group, at increased risk for HIV, hepatitis B and certain other infections that can be transmitted by transfusion. [ Public health These safer sex recommendations are agreed upon by public health officials for women who have sex with women to avoid sexually transmitted infections (STIs): Avoid contact with a partner’s menstrual blood and with any visible genital lesions. Cover sex toys that penetrate more than one persons vagina or anus with a new condom for each person; consider using different toys for each person. Use a barrier (e. g. , latex sheet, dental dam, cut-open condom, plastic wrap) during oral sex. Use latex or vinyl gloves and lubricant for any manual sex that might cause bleeding. [186] These safer sex recommendations are agreed upon by public health officials for men who have sex with men to avoid sexually transmitted infections: Avoid contact with a partners bodily fluids and with any visible genital lesions. Use condoms for anal and oral sex. Use a barrier (e. g. , latex sheet, dental dam, cut-open condom) during anal–oral sex. Cover sex toys that penetrate more than one person with a new condom for each person; consider using different toys for each person and use latex or vinyl gloves and lubricant for any sex that might cause bleeding. Gay and lesbian youth See also: Suicide among LGBT youth Gay and lesbian youth bear an increased risk of suicide, substance abuse, school problems, and isolation because of a hostile and condemning environment, verbal and physical abuse, rejection and isolation from family and peers. [192] Further, LGBT youths are more likely to report psychological and physical abuse by parents or caretakers, and more sexual abuse. Suggested reasons for this disparity are that (1) LGBT youths may be specifically targeted on the basis of their perceived sexual orientation or gender non-conforming appearance, and (2) that risk factors associated with sexual minority status, including discrimination, invisibility, and rejection by family members may lead to an increase in behaviors that are associated with risk for victimization, such as substance abuse, sex with multiple partners, or running away from home as a teenager. [ Lesbian, gay, bisexual, and transgender (LGBT) people in the Philippines have a distinctive culture but limited legal rights. Gays and lesbians are generally tolerated, if not accepted, within Filipino society, but there is still widespread discrimination. The most visible members of the Filipino LGBT culture, the Bakla, are a distinct group in the Philippines. According to the 2002 Young Adult Fertility and Sexuality Survey, 11% of sexually active Filipinos between the ages of 15 and 24 have had sex with someone of the same sex. [1] Filipino poet and critic Lilia Quindoza Santiago has speculated that Filipino culture may have a more flexible concept of gender because kasarian, the Tagalog word for gender, is defined in less binary terms than the English word gender. [2] Kasarian means kind, species, or genus. [3] The English word gender originally also meant kind. Phil. Survey The Philippines has earned its ranking as one of few gay-friendly countries in the world. Of the 39 countries covered by a global survey, only 17 countries had majorities that accepted homosexuality, with the Philippines ranking at number 10 among the 17. Despite its religiosity, the Philippines is one of the countries in the world where the level of public â€Å"acceptance† of homosexuals is high, according to the results of the survey. The survey titled â€Å"The Global Divide on Homosexuality† conducted by the US-based Pew Research Center showed that 73 percent of adult Filipinos agreed with the statement that â€Å"homosexuality should be accepted by society,† up by nine percentage points from 2002. The percentage of Filipinos who said society should not accept gays fell from 33 percent in 2002 to 26 percent this year, it added. This high level of acceptance, which is comparable to that found in secular western Europe, is even higher than those found in Japan (54 percent), South Korea (39 percent) or the United States (60 percent), where some states allow gay marriage. â€Å"Brazilians and Filipinos are considerably more tolerant of homosexuality than their countries’ relatively high levels of religiosity would suggest,† the Pew survey report said. The Philippines bucked the trend found in the survey showing that gays are mostly accepted in rich and secularized countries. â€Å"The survey †¦ finds that acceptance of homosexuality is particularly widespread in countries where religion is less central in people’s lives. These are also among the richest countries in the world,† the Pew report said. â€Å"In contrast, in poorer countries with high levels of religiosity, few believe homosexuality should be accepted by society,† it added. Religiosity scale The Philippines is said to be one of the most religious countries in the world and almost a third of its population lives below the poverty line. In the survey’s â€Å"religiosity scale† where a score of â€Å"3† was the most religious, the Philippines almost got 2. 5. â€Å"Age is also a factor in several countries, with younger respondents offering far more tolerant views than older ones,† the survey report said. And while gender differences are not prevalent, in those countries where they are, women are consistently more accepting of homosexuality than men,† it added. In the Philippines, 78 percent of those aged 18-29 who were interviewed said gays should be accepted, 71 percent for those aged 30-49, and 68 percent for those 50 years old and above, according to the survey. The report also showed that of the eight countries surveyed in the Asia-Pacific region, the Philippines had the second highest acceptance rate next to Australia’s 79 percent. â€Å"In the Asia-Pacific region, where views of homosexuality are mostly negative, more than seven in 10 in Australia and the Philippines say homosexuality should be accepted by society,† the report said. In contrast, only three percent of people in neighboring Indonesia, nine percent in Malaysia and 21 percent in China said homosexuality should be accepted, the report added. Not impressed However, Filipino gay groups were not impressed by the survey results. When asked if the gay community in the Philippines felt accepted, Jonas Bagas, executive director of the TLF Share Collective, said: â€Å"Hardly. † â€Å"I think that the study only reflects the perceived acceptance of the LGBT community based on the high visibility of gay entertainers. It’s acceptance [that is] contingent on how you fit the acceptable stereotype—the gay entertainer, the creative, talented bakla, the lesbian security guard,† Bagas said. â€Å"Once you go outside these stereotypes, that’s when you encounter rejection,† he added. Bagas said a Filipino student in a lesbian relationship faces higher probability of getting kicked out of her school than a student in a heterosexual relationship. â€Å"We still have strong biases against gay sex, which for many is still deemed immoral and unnatural. This attitude fosters inequality in our laws, in education, healthcare and even within the family,† Bagas said. The Pew report said those who conducted the survey had face-to-face interviews with 804 Filipinos aged 18 and above from March 10 to April 3 this year. The interviews were conducted in Tagalog, Cebuano, Ilonggo, Ilocano and Bicolano. The survey had a margin of error of plus or minus 4. 5 percent. Lesbian, gay, bisexual, and transgender (LGBT) people in the Philippines have a distinctive culture but limited legal rights. Gays and lesbians are generally tolerated, if not accepted, within Filipino society, but there is still widespread discrimination. The most visible members of the Filipino LGBT culture, the Bakla, are a distinct group in the Philippines. According to the 2002 Young Adult Fertility and Sexuality Survey, 11% of sexually active Filipinos between the ages of 15 and 24 have had sex with someone of the same sex. [1] Filipino poet and critic Lilia Quindoza Santiago has speculated that Filipino culture may have a more flexible concept of gender because kasarian, the Tagalog word for gender, is defined in less binary terms than the English word gender. [2] Kasarian means kind, species, or genus. [3] The English word gender originally also meant kind. A bakla is a gay man who displays feminine mannerisms, dresses as a woman, or identifies as a woman. The term itself is not the equivalent of the English term gay,[4] but bakla are the most culturally visible subset of gay men in the Philippines. They are often considered a third gender, embodying femaleness (pagkababae) in a male body. [5][6] The term bakla is sometimes used in a derogatory sense, although bakla people have largely embraced it. Bakla individuals are socially and economically integrated into Filipino society and are considered an important part of society. The stereotype of a bakla is a parlorista, a cross-dresser who works in a beauty salon. [7] Miss Gay Philippines is a beauty pageant for bakla. Slang terms for LGBT people and concepts In the Philippines, the term gay is used in reference to any LGBT person. For Filipino gays, the Tagalog phrase paglaladlad ng kapa (unfurling the cape), or more commonly just paglaladlad(unfurling or unveiling) refers to the coming-out process. Tibo, T-Bird and tomboy are derogatory terms for butch lesbians just as bakla is for effeminate gay men. Some lesbians, both butch and femme, use the terms magic or shunggril to refer to themselves. [4] Neutral slang terms for gay men include billy boy, badette, bading, and paminta (straight-acting gay man). While many of these terms are generally considered derogatory, they are sometimes used casually or jokingly within the Filipino gay and lesbian community. For example, gay men often refer to their gay friends as bakla when talking to each other. Swardspeak[edit] Main article: Swardspeak This article may be confusing or unclear to readers. Please help us clarify the article; suggestions may be found on the talk page. (October 2013) Swardspeak, or gay lingo, is a cant slang derived from Englog (a Tagalog-English pidgin) and is used by a number of homosexuals in the Philippines. [12] Swardspeak uses elements fromTagalog, English, Spanish and Japanese, as well as celebrities names and trademark brands, giving them new meanings in different contexts. [13] It is largely localized within gay communities and uses words derived from local languages or dialects, including Cebuano, Hiligaynon, Waray, Bicolano, and/or other Philippine languages. The use of Swardspeak once immediately identified the speaker as homosexual, making it easy for people of that orientation to recognize each other. This created an exclusive group among its speakers and helped them resist cultural assimilation. More recently, though, straight people have also started to use this way of speaking, particularly in industries dominated by gays, such as the fashion and film industries. LGBT Politics: In the Philippines, the Communist Party of the Philippines Marxist-Leninist and Maoist revolutionary proletarian party in the Philippines are the one and first to introduce and promote the Lesbian, Gay, Bisexual and Transgender. They recognize the LGBT as part of the bulk of the masses that can encourage and recruit for their revolutionary work. The revolutionary leader admitted that in their rank. The wide spread of sexual intercourse within their rank and same sex that brought their party principle to set a guideline for those belong with the LGBTs. They also allow to married their fellow same sex revolutionary party member as long it will not affect their revolutionary task in the party organization. Document of the CPP-MLM guideline Gabay Para sa Rebolusyunaryong Pakikipagrelasyon at Pagpapakasal . Same-sex relationships People with a homosexual orientation can express their sexuality in a variety of ways, and may or may not express it in their behaviors. [1] Many have sexual relationships predominately with people of their own gender identity, though some have sexual relationships with those of the opposite gender, bisexual relationships, or none at all (celibate). [1] The Kinsey scale attempts to describe a persons sexual history or episodes of their sexual activity at a given time. It uses a scale from 0, meaning exclusively heterosexual, to 6, meaning exclusively homosexual. It is based on actual sexual behavior surveys. Research indicates that many lesbians and gay men want, and succeed in having, committed and durable relationships. For example, survey data indicate that between 40% and 60% of gay men and between 45% and 80% of lesbians are currently involved in a romantic relationship. [110] Survey data also indicate that between 18% and 28% of gay couples and between 8% and 21% of lesbian couples in the U. S. have lived together ten or more years. [110] Studies have found same-sex and opposite-sex couples to be equivalent to each other in measures of satisfaction and commitment in relationships, that age and gender are more reliable than sexual orientation as a predictor of satisfaction and commitment to a relationship, and that people who are heterosexual or homosexual share comparable expectations and ideals with regard to romantic relationships. Sexual orientation free essay sample Historical and Scientific Perspectives on Homosexuality Shineaka Collins PSY/265 February 5, 2012 Nicole Pansey Historical and Scientific Perspectives on Homosexuality Historical and scientific perspectives on homosexuality may have shaped the way gay individuals perceive themselves because when you research the historical moments depending on your religion it may have been accepted. In ancient Greece it was frequent that men had relationships with young boys. Although the Greeks had their own perspective of male on male relationships the Christians and the Jews had another. The Romans also believed male on male relationships were acceptable; the men were flamboyant and did not hide their homosexuality. The Christians and Jews believed that male on male relations was sin of Sodom. Sodom is the city that God destroyed, even though it was never proven why God destroyed Sodom. I know I was born and raised a in a Christian family, and we were forbidden to believe same sex relationships were acceptable. We will write a custom essay sample on Sexual orientation or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page My family always preached according to The Holy Bible and it explained that God destroyed Sodom because same sex relations were happening there. Also we have cross-cultural perspectives that include the Swans of North Africa; they believed that the younger men should engage in sex with older men. Their own father arranged for them to be with older males, and then when they have reached puberty most of them married women. Last the Sambian people of New Guinea believe that semen boost their young boys strength and virility. Older men insert semen into young boys anally or have them drink it. The Sambians’ believe this will increase manhood. Scientifically researchers believe genes, hormones and brain differences have their own perspective of why people are homosexual. A study on hormones proved there were no differences but in the genes there was a difference. There is evidence that there is brain difference in homosexuals and heterosexuals showing in neuropsychological, and neuroanatomical, and hormone response (Pinel, 2007). Furthermore, if you are a homosexual the healthiest thing to do is come out of the closet. Coming out of the closet is a saying that people use about others that are afraid to express their sexuality. This is the hardest part about living as a homosexual, because you are afraid that some people may not accept your identity. If you come from a Christian family this would be one of the hardest things you would have to do in life. Most people come out during their teenage years, because this is when we begin to learn more about our sexuality and identity. Most homosexual people tell their friends before they tell their family, because they are afraid of rejection. Some people live double lives, doing this they do not want to be seen in public with their partner because they are afraid of what society might think. Basically they only want the company of their partner in closed doors and keep them a secret from the world. These types of homosexuals are still in the closet but are worried about what people may think of them if they come out. Consequently coming out will take some adjustment as well. You may have to cope with peoples negative actions toward you, because they may have a different belief about homosexuals, or they may be shocked at what your preference is. Some people may not be able to accept the fact about you sexual preference or your gender identity. According to D’Augelli who studies homosexuality among the young says â€Å"many adults might be surprised at the secret that really lurks in the psyches of gay teens†. â€Å"The remarkable fact is, most are quite conventional. They want long-term relationships and children† (USA Today) 2007. Coming out does not solve the problem it may create new ones, but you have to look past all the negativity so that you can continue with your life and relieve all the stress, and this will boost your self-esteem because you are being who you are. Homosexuals have to adjust their lives in different situations. When you are out of the closet people may ask you certain questions about your sexual preference and why did you choose to be gay. Also you have to be conscience about being in the military. If this is something you had as a goal you are not able to express your sexual preference in the military. Today people are more understanding, and tolerant to homosexuals’ lifestyles. There are many support groups to help people cope with their sexuality and gender identities. Historic and scientific perspectives have reflected on my sexual orientation in one way that I was born and raised as a Christian, and how I raise my family by The Holy Bible. I believe that homosexuality is a sin but I cannot judge anyone. I am a heterosexual woman never looking at another woman in a homosexual way has ever crossed my mind or is acceptable in my religion or within my family. My grandmother is our Pastor at the church of Living God and I witnessed her not accepting a homosexual into our church unless he was coming to be forgiven and helped to become a heterosexual. He testified that he was gay and wanted to be accepted by the church and my grandmother asked him to leave. I was shocked, and as she proceeded with service she explained that being a homosexual was not acceptable God created man to be with woman to conceive children which is the only reason we should be having sexual relations to create children not for pleasure.